CDK5 (2E8) Mouse mAb

261047

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: N261047

Product Name: Anti-CDK5 (2E8) Mouse Monoclonal Antibody

Synonyms: Cdk 5; Cdk5; CDK5_HUMAN; Cell division protein kinase 5; Crk6; Cyclin dependent kinase 5; Cyclin-dependent kinase 5; Protein kinase CDK5 splicing; PSSALRE; Serine threonine protein kinase PSSALRE; Serine/threonine-protein kinase PSSALRE; Tau protein kinase II catalytic subunit; TPKII catalytic subunit.

UNIPROT ID: Q00535

Background: Activated by cyclins but by p35 (CDK5R1) and p39. An important regulator of neuronal positioning during brain development. May also play a role in synaptogenesis and neurotransmission. Substrates include TAU, MAP2, NF-H and -M, Nudel, PDE6, beta-catenin, amphyphysin, dynamin I, synapsin 1, Munc-18, and NMDA receptor 2A. Plays a role in myogenesis, haematopoietic cell differentiation, spermatogenesis, insulin secretion, and lens differentiation.

Immunogen: Purified recombinant human CDK5(N-terminus) protein fragments expressed in E.coli.

Applications: WB,ICC/IF

Recommended Dilutions: WB: 1/500-1/1000 IF: 1/50-1/200

Host Species: Mouse

Clonality: Mouse Monoclonal

Clone ID: 2E8-F9-B7-C11

MW: Calculated MW: 33 kDa; Observed MW: 36 kDa

Isotype: IgG1

Purification: Affinity Purified

Species Reactivity: Human,Mouse,Rat,Monkey

Conjugation: Unconjugated

Modification: Unmodified

Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide

Research Areas: NeuroscienceyyyyyAlzheimer's disease

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Immunocytochemistry analysis of CDK5 in HeLa cells using CDK5 antibody.

Western blot analysis of CDK5(Nterminus) in 3T3, Hela, PC-12, COS7, Jurkat and K562 lysates using Cdk5 antibody.

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