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BTK (5B12) Mouse mAb

261049

Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:   N261049
Product Name:   Anti-BTK (5B12) Mouse Monoclonal Antibody
Synonyms:   BTK; AGMX1; ATK; BPK; Tyrosine-protein kinase BTK; Agammaglobulinaemia tyrosine kinase; ATK; B-cell progenitor kinase; BPK; Bruton tyrosine kinase
UNIPROT ID:   Q06187
Background:    Defects in the Bruton tyrosine kinase (BTK) gene cause Agammaglobulinemia. Agammaglobulinemia is an X-linked immunodeficiency characterized by failure to produce mature B lymphocyte cells and associated with a failure of Ig heavy chain rearrangement.
Immunogen:    Purified recombinant human BTK protein fragments expressed in E.coli.
Applications:    WB,IP
Recommended Dilutions:    WB: 1/500-1/1000 IP: 1/20
Host Species:    Mouse
Clonality:    Mouse Monoclonal
Clone ID:    5B12-C9-F10
MW:    Calculated MW: 76 kDa; Observed MW: 76 kDa
Isotype:    IgG1
Purification:    Affinity Purified
Species Reactivity:    Human
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunoprecipitation analysis of BTK (5B12) in Raji lysates using BTK antibody.

Western blot analysis of BTK in Daudi, Jurkat(BTK negative), K562, Ramos and Raji lysates using BTK antibody.
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