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Rad9 Mouse mAb

261085

Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:   N261085
Product Name:   Anti-Rad9 Mouse Monoclonal Antibody
Synonyms:   RAD9; hRAD9
UNIPROT ID:   Q99638
Background:    This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair. This protein possesses 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Immunogen:    Purified recombinant human RAD9A protein fragments expressed in E.coli
Applications:    WB,IP
Recommended Dilutions:    WB: 1/500-1/1000 IP: 1/20
Host Species:    Mouse
Clonality:    Mouse Monoclonal
Clone ID:    3A3-A7-F8
MW:    Calculated MW: 43 kDa; Observed MW: 60 kDa
Isotype:    IgG2b
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse,Rat,Monkey
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunoprecipitation analysis of Rad9 in Hela and 3T3 lysates using RAD9A antibody.

Western blot analysis of RAD9A in Hela, MCF-7, 3T3, COS7 and rat testis lysates using RAD9A antibody.
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