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MMP2 (3A8) Mouse mAb

261112

Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:   N261112
Product Name:   Anti-MMP2 (3A8) Mouse Monoclonal Antibody
Synonyms:   MMP2; CLG4A; 72 kDa type IV collagenase; 72 kDa gelatinase; Gelatinase A; Matrix metalloproteinase-2; MMP-2; TBE-1
UNIPROT ID:   P08253
Background:    MMP2 Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-|-Leu bond. Appears to have a role in myocardial cell death pathways.
Immunogen:    Purified recombinant human MMP-2 protein expressed in E.coli.
Applications:    WB,ICC/IF
Recommended Dilutions:    WB: 1/500-1/1000 IF: 1/50-1/200
Host Species:    Mouse
Clonality:    Mouse Monoclonal
Clone ID:    3A8-C1-E8
MW:    Calculated MW: 74 kDa; Observed MW: 74 kDa
Isotype:    IgG1
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunofluorescence analysis of MMP2 (3A8) in Hela using MMP2 antibody,and DAPI (blue).

Western blot analysis of MMP2 (3A8) in CHO-K1 (B) and CHO-K1 transfected by MMP2 fragment(A) lysates using MMP2 antibody.

Western blot analysis of MMP2 (3A8) in Raw264.7 lysates using MMP2 antibody.
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