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Size：100 μl
Price：$ 349
Brand：NewEast 
Place of Origin：USA
Immunogen：
| Cat.#: N261122 | ||||
| Product Name: Anti-JNK1 (1A4) Mouse Monoclonal Antibody | ||||
| Synonyms: AI849689; c Jun N terminal kinase 1; C-JUN kinase 1; c-Jun N-terminal kinase 1; EC 2.7.11.24; JAK 1A; JAK1A; JNK 1; JNK 46; JNK; JNK-46; JNK1A2; JNK21B1/2; MAP kinase 8; MAPK 8; MAPK8; Mitogen activated protein kinase 8; Mitogen-activated protein kinase 8; MK08_HUMAN; p54 gamma; PRKM 8; PRKM8; Protein kinase JNK1; Protein kinase; mitogen-activated; 8; SAPK 1; SAPK gamma; SAPK1; Stress activated protein kinase JNK1; Stress-activated protein kinase 1; Stress-activated protein kinase JNK1; Tyrosine protein kinase JAK1 . | ||||
| UNIPROT ID: P45983 | ||||
| Background: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Apr 2016] | ||||
| Immunogen: Purified recombinant human JNK1 protein fragments expressed in E.coli. | ||||
| Applications: WB,ICC/IF | ||||
| Recommended Dilutions: WB: 1/500-1/1000 IF: 1/50-1/200 | ||||
| Host Species: Mouse | ||||
| Clonality: Mouse Monoclonal | ||||
| Clone ID: 1A4-C5-F11 | ||||
| MW: Calculated MW: 48 kDa; Observed MW: 46,54 kDa | ||||
| Isotype: IgG2a | ||||
| Purification: Affinity Purified | ||||
| Species Reactivity: Human,Mouse,Rat | ||||
| Conjugation: Unconjugated | ||||
| Modification: Unmodified | ||||
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide | ||||
| Research Areas: Signal Transduction | ||||
| Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||||
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