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SIRT1 (2G10) Mouse mAb

261128

Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:   N261128
Product Name:   Anti-SIRT1 (2G10) Mouse Monoclonal Antibody
Synonyms:   SIRT1; SIR2L1; NAD-dependent protein deacetylase sirtuin-1; hSIRT1; Regulatory protein SIR2 homolog 1; SIR2-like protein 1; hSIR2
UNIPROT ID:   Q96EB6
Background:    This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA.
Immunogen:    Purified recombinant human SIRT1 protein fragments expressed in E.coli.
Applications:    WB,IP
Recommended Dilutions:    WB: 1/500-1/1000 IP: 1/20
Host Species:    Mouse
Clonality:    Mouse Monoclonal
Clone ID:    2G10-F4-D9
MW:    Calculated MW: 82 kDa; Observed MW: 120 kDa
Isotype:    IgG2b
Purification:    Affinity Purified
Species Reactivity:    Human
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunoprecipitation analysis of SIRT1 (2G10) in Hela lysates using SIRT1 antibody.

Western blot analysis of SIRT1 in Hela, Jurkat, Ramos, A549 and CEM lysates using SIRT1 antibody.
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