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Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:
Cat.#: N261176 | ||||
Product Name: Anti-MLH1 (4C1) Mouse Monoclonal Antibody | ||||
Synonyms: MLH1; COCA2; DNA mismatch repair protein Mlh1; MutL protein homolog 1 | ||||
UNIPROT ID: P40692 | ||||
Background: This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Alternatively spliced transcript variants encoding different isoforms have been described, but their full-length natures have not been determined. | ||||
Immunogen: Purified recombinant fragment of MLH1 (aa381-483) expressed in E. Coli. | ||||
Applications: WB,ICC/IF | ||||
Recommended Dilutions: WB: 1/500-1/1000 IF: 1/50-1/200 | ||||
Host Species: Mouse | ||||
Clonality: Mouse Monoclonal | ||||
Clone ID: 4C1-D9-C7 | ||||
MW: Calculated MW: 85 kDa; Observed MW: 85 kDa | ||||
Isotype: IgG1 | ||||
Purification: Ascitic Fluid | ||||
Species Reactivity: Human,Monkey | ||||
Conjugation: Unconjugated | ||||
Modification: Unmodified | ||||
Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide | ||||
Research Areas: Epigenetics and Nuclear Signaling | ||||
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||||
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Bioactive Transmembrane Proteins Antibodies for Transmembrane Proteins G Protein | GTPase