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MLH1 (4C1) Mouse mAb

261176

Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:   N261176
Product Name:   Anti-MLH1 (4C1) Mouse Monoclonal Antibody
Synonyms:   MLH1; COCA2; DNA mismatch repair protein Mlh1; MutL protein homolog 1
UNIPROT ID:   P40692
Background:    This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Alternatively spliced transcript variants encoding different isoforms have been described, but their full-length natures have not been determined.
Immunogen:    Purified recombinant fragment of MLH1 (aa381-483) expressed in E. Coli.
Applications:    WB,ICC/IF
Recommended Dilutions:    WB: 1/500-1/1000 IF: 1/50-1/200
Host Species:    Mouse
Clonality:    Mouse Monoclonal
Clone ID:    4C1-D9-C7
MW:    Calculated MW: 85 kDa; Observed MW: 85 kDa
Isotype:    IgG1
Purification:    Ascitic Fluid
Species Reactivity:    Human,Monkey
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of MLH1 (4C1) in SW48, 293T, Jurkat and Hela lysates using MLH1 (4C1) antibody

Immunocytochemistry analysis of MLH1 (4C1) in HeLa cells using MLH1 antibody.

Western blot analysis of MLH1 (4C1) in Hela, Jurkat, 293T and SW480 lysates using MLH1 (4C1) antibody
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