PYK2 (4B4) Mouse mAb

261186

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: N261186

Product Name: Anti-PYK2 (4B4) Mouse Monoclonal Antibody

Synonyms: PTK2B; FAK2; PYK2; RAFTK; Protein-tyrosine kinase 2-beta; Calcium-dependent tyrosine kinase; CADTK; Calcium-regulated non-receptor proline-rich tyrosine kinase; Cell adhesion kinase beta; CAK-beta; CAKB; Focal adhesion kinase 2; FADK 2; Pro

UNIPROT ID: Q14289

Background: PYK2 a nonreceptor tyrosine kinase of the Fak family. Predominantly expressed in the cells derived from hematopoietic lineages and in the central nervous system. PYK2 is one of the signaling mediators for G-protein-coupled receptors. Involved in calcium induced regulation of ion channel and activation of the map kinase signaling pathway. Interacts with the SH2 domain of Grb2.

Immunogen: Purified recombinant fragment of PYK2 (aa815-997) expressed in E. Coli.

Applications: WB,IHC-P

Recommended Dilutions: WB: 1/500-1/1000 IHC: 1/50-1/100

Host Species: Mouse

Clonality: Mouse Monoclonal

Clone ID: 4B4-D0-F3

MW: Calculated MW: 116 kDa; Observed MW: 116 kDa

Isotype: IgG2a

Purification: Ascitic Fluid

Species Reactivity: Human

Conjugation: Unconjugated

Modification: Unmodified

Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide

Research Areas: Signal Transduction

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human Tonsil tissues using PYK2 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Western blot analysis of Pyk2 in A549, Ramos, Jurkat, THP-1 and Raji lysates using Pyk2 antibody.

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