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LYRIC (2E4) Mouse mAb

261194

Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:   N261194
Product Name:   Anti-LYRIC (2E4) Mouse Monoclonal Antibody
Synonyms:   MTDH; AEG1; LYRIC; Protein LYRIC; 3D3/LYRIC; Astrocyte elevated gene-1 protein; AEG-1; Lysine-rich CEACAM1 co-isolated protein; Metadherin; Metastasis adhesion protein
UNIPROT ID:   Q86UE4
Background:    Downregulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Activates the nuclear factor kappa-B (NF-kappa-B) transcription factor. Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion.
Immunogen:    Purified recombinant fragment of human Metadherin expressed in E. Coli.
Applications:    WB,IHC-P,FC
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 FC: 1/50-1/100
Host Species:    Mouse
Clonality:    Mouse Monoclonal
Clone ID:    2E4-D8-D11
MW:    Calculated MW: 64 kDa; Observed MW: 64 kDa
Isotype:    IgG1
Purification:    Ascitic Fluid
Species Reactivity:    Human
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Flow cytometry analysis of Hela cells stained with Metadherin antibody(green) and negative control(purple).

Western blot analysis of Lyric/Metadherin in Jurkat, A549, MCF-7 and Hela lysates using Lyric/Metadherin antibody.

Immunohistochemistry analysis of paraffin-embedded Human Liver tissues using Metadherin antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
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