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ABCB5 (8D2) Mouse mAb

261227

Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:   N261227
Product Name:   Anti-ABCB5 (8D2) Mouse Monoclonal Antibody
Synonyms:   ABCB5 P-gp; ATP binding cassette sub family B (MDR/TAP) member 5; P glycoprotein ABCB5
UNIPROT ID:   Q2M3G0
Background:    Drug efflux transporter present in a number of stem cells that acts as a regulator of cellular differentiation. Able to mediate efflux from cells of the rhodamine dye and of the therapeutic drug doxorubicin. Specifically present in limbal stem cells, where it plays a key role in corneal development and repair.
Immunogen:    Synthetic Peptide of ABCB5
Applications:    WB,ICC/IF
Recommended Dilutions:    WB: 1/500-1/1000 IF: 1/50-1/200
Host Species:    Mouse
Clonality:    Mouse Monoclonal
Clone ID:    8D2-2B8-4E8
MW:    Calculated MW: 139 kDa; Observed MW: 90 kDa
Isotype:    IgG1
Purification:    Affinity Purified
Species Reactivity:    Human
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunocytochemistry analysis of ABCB5 (8D2) (green) in Hela using ABCB5 (8D2) antibody ,and DAPI(blue)

Western blot analysis of ABCB5 in K562 lysates using ABCB5 antibody.

Western blot analysis of ABCB5 (8D2) in HepG2, K562 lysates using ABCB5 (8D2) antibody.
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