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Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:
Cat.#: N261247 | ||||
Product Name: Anti-EGFR (5E9) Mouse Monoclonal Antibody | ||||
Synonyms: EGFR; ERBB; ERBB1; HER1; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1 | ||||
UNIPROT ID: P00533 | ||||
Background: EGFR is a receptor tyrosine kinase. Receptor for epidermal growth factor (EGF) and related growth factors including TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. . A single-pass transmembrane tyrosine kinase. Ligand binding to this receptor results in receptor dimerization, autophosphorylation (in trans), activation of various downstream signaling molecules and lysosomal degradation. | ||||
Immunogen: Synthetic Peptide of EGFR | ||||
Applications: WB,IP | ||||
Recommended Dilutions: WB: 1/500-1/1000 IP: 1/20 | ||||
Host Species: Mouse | ||||
Clonality: Mouse Monoclonal | ||||
Clone ID: 5E9-10B8-8B9 | ||||
MW: Calculated MW: 134 kDa; Observed MW: 170 kDa | ||||
Isotype: IgG1 | ||||
Purification: Affinity Purified | ||||
Species Reactivity: Human | ||||
Conjugation: Unconjugated | ||||
Modification: Unmodified | ||||
Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide | ||||
Research Areas: Signal Transduction | ||||
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||||
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Bioactive Transmembrane Proteins Antibodies for Transmembrane Proteins G Protein | GTPase