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Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:
Cat.#: N261262 | ||||
Product Name: Anti-alpha Smooth Muscle Actin (3G2) Mouse Monoclonal Antibody | ||||
Synonyms: ACTA2; ACTSA; ACTVS; GIG46; Actin; aortic smooth muscle; Alpha-actin-2; Cell growth-inhibiting gene 46 protein; α-SMA | ||||
UNIPROT ID: P62736 | ||||
Background: Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Defects in ACTA2 are the cause of aortic aneurysm familial thoracic type 6 (AAT6) [MIM:611788]. They are primarily associated with a characteristic histologic appearance known as 'medial necrosis' or 'Erdheim cystic medial necrosis' in which there is degeneration and fragmentation of elastic fibers, loss of smooth muscle cells, and an accumulation of basophilic ground substance. | ||||
Immunogen: Synthetic Peptide of α-SMA | ||||
Applications: WB,IHC-F,IHC-P,ICC/IF | ||||
Recommended Dilutions: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 | ||||
Host Species: Mouse | ||||
Clonality: Mouse Monoclonal | ||||
Clone ID: 3G2-2G9-4G5 | ||||
MW: Calculated MW: 42 kDa; Observed MW: 42 kDa | ||||
Isotype: IgG1 | ||||
Purification: Affinity Purified | ||||
Species Reactivity: Human,Mouse,Rat | ||||
Conjugation: Unconjugated | ||||
Modification: Unmodified | ||||
Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide | ||||
Research Areas: Signal Transduction | ||||
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||||
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