p53 (2D10) Mouse mAb

261271

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: N261271

Product Name: Anti-p53 (2D10) Mouse Monoclonal Antibody

Synonyms: TP53; P53; Cellular tumor antigen p53; Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53

UNIPROT ID: P04637

Background: Tumor protein p53, a nuclear protein, plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains.

Immunogen: Synthetic Peptide of p53

Applications: WB,IHC-F,IHC-P,ICC/IF

Recommended Dilutions: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200

Host Species: Mouse

Clonality: Mouse Monoclonal

Clone ID: 2D10-1E9-1D3

MW: Calculated MW: 44 kDa; Observed MW: 53 kDa

Isotype: IgG1

Purification: Affinity Purified

Species Reactivity: Human

Conjugation: Unconjugated

Modification: Unmodified

Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide

Research Areas: Cell Biology

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human colon cancer tissue using p53 (2D10) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.	Immunofluorescence analysis of p53 in Hela using p53 (2D10) antibody (Left) and DAPI (Right).
Western blot analysis of p53 (2D10) in T47D and COS7 lysates using p53 (2D10) antibody

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p53 (2D10) Mouse mAb

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