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Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:
Cat.#: N261306 | ||
Product Name: Anti-Phospho-AKT (Ser473) (8A9) Mouse Monoclonal Antibody | ||
Synonyms: AKT1; PKB; RAC; RAC-alpha serine/threonine-protein kinase; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alpha | ||
UNIPROT ID: P31749 | ||
Background: Akt, also referred to as PKB or Rac, plays a critical role in controlling survival and apoptosis. This protein kinase is activated by insulin and various growth and survival factors to function in a wortmannin-sensitive pathway involving PI3 kinase. Akt is activated by phospholipid binding and activation loop phosphorylation at Thr308 by PDK1 and by phosphorylation within the carboxy terminus at Ser473. | ||
Immunogen: Synthetic peptide conjugated to KLH. | ||
Applications: WB,IHC-P | ||
Recommended Dilutions: WB: 1/500-1/1000 IHC: 1/50-1/100 | ||
Host Species: Mouse | ||
Clonality: Mouse Monoclonal | ||
Clone ID: 8A9-4C4-3F3 | ||
MW: Calculated MW: 56 kDa; Observed MW: 60 kDa | ||
Isotype: IgG1 | ||
Purification: Affinity Purified | ||
Species Reactivity: Human | ||
Conjugation: Unconjugated | ||
Modification: Phosphorylated | ||
Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide | ||
Research Areas: Neuroscience | ||
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||
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Bioactive Transmembrane Proteins Antibodies for Transmembrane Proteins G Protein | GTPase