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Phospho-ERK1/2 (Tyr222/Tyr205) (1H4) Mouse mAb

261315

Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:   N261315
Product Name:   Anti-Phospho-ERK1/2 (Tyr222/Tyr205) (1H4) Mouse Monoclonal Antibody
Synonyms:   MAPK1/MAPK3
UNIPROT ID:   P27361/P28482
Background:    Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.
Immunogen:    Synthetic peptide conjugated to KLH.
Applications:    IHC-P
Recommended Dilutions:    IHC: 1/50-1/100
Host Species:    Mouse
Clonality:    Mouse Monoclonal
Clone ID:    1H4-6D7-9D8
MW:    -
Isotype:    IgG1
Purification:    Affinity Purified
Species Reactivity:    Human,Rat,Mouse
Conjugation:    Unconjugated
Modification:    Phosphorylated
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemical analysis of paraffin-embedded Human tonsils using Phospho-ERK1/2 (Tyr222/Tyr205) (1H4) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Immunohistochemistry analysis of paraffin-embedded Human Colon Carcinoma Tissue using Phospho-ERK1/2 (Tyr222/Tyr205) (1H4) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
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