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Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:
Cat.#: N261330 |
Product Name: Anti-PTEN (7H2) Mouse Monoclonal Antibody |
Synonyms: PTEN; MMAC1; TEP1; Phosphatidylinositol 3; 4; 5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; Mutated in multiple advanced cancers 1; Phosphatase and tensin homolog |
UNIPROT ID: P60484 |
Background: Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3-phosphate and inositol 1,3,4,5-tetrakisphosphate with order of substrate preference in vitro PtdIns(3,4,5)P3 > PtdIns(3,4)P2 > PtdIns3P > Ins(1,3,4,5)P4. |
Immunogen: Synthetic peptide conjugated to KLH. |
Applications: IHC-P |
Recommended Dilutions: IHC: 1/50-1/100 |
Host Species: Mouse |
Clonality: Mouse Monoclonal |
Clone ID: 7H2-6G9-6H5 |
MW: - |
Isotype: IgG1 |
Purification: Affinity Purified |
Species Reactivity: Human |
Conjugation: Unconjugated |
Modification: Unmodified |
Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide |
Research Areas: Cell Biology |
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin-embedded Human Colon Carcinoma Tissue using PTEN (7H2) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. |
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Bioactive Transmembrane Proteins Antibodies for Transmembrane Proteins G Protein | GTPase