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ATM (9F7) Mouse mAb

261343

Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:   N261343
Product Name:   Anti-ATM (9F7) Mouse Monoclonal Antibody
Synonyms:   ATM; Serine-protein kinase ATM; Ataxia telangiectasia mutated; A-T mutated
UNIPROT ID:   Q13315
Background:    The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability.
Immunogen:    Synthetic peptide conjugated to KLH.
Applications:    IHC-P
Recommended Dilutions:    IHC: 1/50-1/100
Host Species:    Mouse
Clonality:    Mouse Monoclonal
Clone ID:    9F7-2B5-5G2
MW:    -
Isotype:    IgG1
Purification:    Affinity Purified
Species Reactivity:    Human,Rat,Mouse
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemical analysis of paraffin-embedded Human tonsils using ATM (9F7) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Immunohistochemistry analysis of paraffin-embedded Human Colon Carcinoma Tissue using ATM (9F7) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
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