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Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:
Cat.#: N261351 | ||
Product Name: Anti-JAK2 (6B4) Mouse Monoclonal Antibody | ||
Synonyms: JAK2; Tyrosine-protein kinase JAK2; Janus kinase 2; JAK-2 | ||
UNIPROT ID: O60674 | ||
Background: Phosphorylated STATs then form homodimer or heterodimers and translocate to the nucleus to activate gene transcription. For example, cell stimulation with erythropoietin (EPO) during erythropoiesis leads to JAK2 autophosphorylation, activation, and its association with erythropoietin receptor (EPOR) that becomes phosphorylated in its cytoplasmic domain. Then, STAT5 (STAT5A or STAT5B) is recruited, phosphorylated and activated by JAK2. | ||
Immunogen: Synthetic peptide conjugated to KLH. | ||
Applications: IHC-P | ||
Recommended Dilutions: IHC: 1/50-1/100 | ||
Host Species: Mouse | ||
Clonality: Mouse Monoclonal | ||
Clone ID: 6B4-8G2-1C4 | ||
MW: - | ||
Isotype: IgG1 | ||
Purification: Affinity Purified | ||
Species Reactivity: Human,Rat,Mouse | ||
Conjugation: Unconjugated | ||
Modification: Unmodified | ||
Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide | ||
Research Areas: Cell Biology | ||
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||
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Bioactive Transmembrane Proteins Antibodies for Transmembrane Proteins G Protein | GTPase