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Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:
Cat.#: N261378 | ||||||
Product Name: Anti-GRP78 BiP (6H7) Mouse Monoclonal Antibody | ||||||
Synonyms: HSPA5; GRP78; 78 kDa glucose-regulated protein; GRP-78; Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78; Heat shock 70 kDa protein 5; Immunoglobulin heavy chain-binding protein; BiP | ||||||
UNIPROT ID: P11021 | ||||||
Background: When Chinese hamster K12 cells are starved of glucose, the synthesis of several proteins, called glucose-regulated proteins (GRPs), is markedly increased. Hendershot et al. (1994) (PubMed 8020977) pointed out that one of these, GRP78 (HSPA5), also referred to as 'immunoglobulin heavy chain-binding protein' (BiP), is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER). | ||||||
Immunogen: Synthetic peptide conjugated to KLH. | ||||||
Applications: WB,IHC-P | ||||||
Recommended Dilutions: WB: 1/500-1/1000 IHC: 1/50-1/100 | ||||||
Host Species: Mouse | ||||||
Clonality: Mouse Monoclonal | ||||||
Clone ID: 6H7-4B1-9H4 | ||||||
MW: Calculated MW: 72 kDa; Observed MW: 78 kDa | ||||||
Isotype: IgG1 | ||||||
Purification: Affinity Purified | ||||||
Species Reactivity: Human,Mouse,Rat | ||||||
Conjugation: Unconjugated | ||||||
Modification: Unmodified | ||||||
Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide | ||||||
Research Areas: Tags & Cell Markers | ||||||
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||||||
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Bioactive Transmembrane Proteins Antibodies for Transmembrane Proteins G Protein | GTPase