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Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:
Cat.#: N261418 |
Product Name: Anti-HDAC2 (2D9) Mouse Monoclonal Antibody |
Synonyms: HDAC2; Histone deacetylase 2; HD2 |
UNIPROT ID: Q92769 |
Background: In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino-terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. |
Immunogen: Purified recombinant human HDAC2 protein fragments expressed in E.coli. |
Applications: WB,ICC/IF |
Recommended Dilutions: WB: 1/500-1/1000 IF: 1/50-1/200 |
Host Species: Mouse |
Clonality: Mouse Monoclonal |
Clone ID: 2D9-F6-G7 |
MW: Calculated MW: 55 kDa; Observed MW: 60 kDa |
Isotype: IgG2b |
Purification: Affinity Purified |
Species Reactivity: Human,Mouse,Rat,Monkey |
Conjugation: Unconjugated |
Modification: Unmodified |
Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide |
Research Areas: Epigenetics and Nuclear Signaling |
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing |
Western blot analysis of HDAC2 in THP-1, SH-SY5Y, K562, COS7, C6, 3T3 and Hela lysates using HDAC2 antibody. |
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