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Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:
Cat.#: N261450 | ||||
Product Name: Anti-Phospho-Histone H2A.X (Ser139) (2A9) Mouse Monoclonal Antibody | ||||
Synonyms: H2A.X; H2AFX; H2a/x; HIST5-2AX; Histone H2A.X; gamma H2A.X | ||||
UNIPROT ID: P16104 | ||||
Background: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. | ||||
Immunogen: Synthetic phosphopeptide corresponding to residues surrounding Ser139 of human H2A.X. | ||||
Applications: WB,ICC/IF | ||||
Recommended Dilutions: WB: 1/500-1/1000 IF: 1/50-1/200 | ||||
Host Species: Mouse | ||||
Clonality: Mouse Monoclonal | ||||
Clone ID: 2A9-B5 | ||||
MW: Calculated MW: 15 kDa; Observed MW: 15 kDa | ||||
Isotype: IgG2a | ||||
Purification: Affinity Purified | ||||
Species Reactivity: Human,Mouse | ||||
Conjugation: Unconjugated | ||||
Modification: Phosphorylated | ||||
Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide | ||||
Research Areas: Epigenetics and Nuclear Signaling | ||||
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||||
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