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AIF (8H1) Mouse mAb

261456

Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:   N261456
Product Name:   Anti-AIF (8H1) Mouse Monoclonal Antibody
Synonyms:   AIFM1; AIF; PDCD8; Apoptosis-inducing factor 1; mitochondrial; Programmed cell death protein 8
UNIPROT ID:   O95831
Background:    This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation.
Immunogen:    Purified recombinant human AIF protein fragments expressed in E.coli.
Applications:    WB,ICC/IF
Recommended Dilutions:    WB: 1/500-1/1000 IF: 1/50-1/200
Host Species:    Mouse
Clonality:    Mouse Monoclonal
Clone ID:    8H1-B10-A12
MW:    Calculated MW: 67 kDa; Observed MW: 67 kDa
Isotype:    IgG2a
Purification:    Affinity Purified
Species Reactivity:    Human
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    apoptosis - Caspase family
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunocytochemistry analysis of AIF (8H1) in HeLa using AIF antibody.

Western blot analysis of AIF (8H1) in Hela, Ramos, HepG2, MCF-7 and Jurkat lysates using AIF antibody.
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