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CRM1 Rabbit mAb

262068

Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:

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Product Description Reference citations(0) Related Products
Cat.#:   N262068
Product Name:   Anti-CRM1 Rabbit Monoclonal Antibody
Synonyms:   XPO1; CRM1; Exportin-1; Exp1; Chromosome region maintenance 1 protein homolog
UNIPROT ID:   O14980
Background:    Mediates the nuclear export of cellular proteins (cargos) bearing a leucine-rich nuclear export signal (NES) and of RNAs. In the nucleus, in association with RANBP3, binds cooperatively to the NES on its target protein and to the GTPase RAN in its active GTP-bound form (Ran-GTP). Docking of this complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins.
Immunogen:    A synthetic peptide of human CRM1
Applications:    WB,ICC/IF
Recommended Dilutions:    WB: 1/500-1/1000 IF: 1/50-1/200
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R03-4G6
MW:    Calculated MW: 123 kDa; Observed MW: 123 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of CRM1 in C6, Hela lysates using CRM1 antibody.

Immunocytochemistry analysis of CRM1 (green) in A549 using CRM1 antibody,and DAPI(blue).
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