DAPK2 Rabbit mAb

262113

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: N262113

Product Name: Anti-DAPK2 Rabbit Monoclonal Antibody

Synonyms: DAPK2; Death-associated protein kinase 2; DAP kinase 2; DAP-kinase-related protein 1; DRP-1

UNIPROT ID: Q9UIK4

Background: Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell death signals, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Acts as a mediator of anoikis and a suppressor of beta-catenin-dependent anchorage-independent growth of malignant epithelial cells. May play a role in granulocytic maturation (PubMed:17347302). Regulates granulocytic motility by controlling cell spreading and polarization (PubMed:24163421).

Immunogen: A synthetic peptide of human DAPK2

Applications: WB,IHC-P

Recommended Dilutions: WB: 1/500-1/1000 IHC: 1/50-1/100

Host Species: Rabbit

Clonality: Rabbit Monoclonal

Clone ID: R09-8F2

MW: Calculated MW: 43 kDa; Observed MW: 43 kDa

Isotype: IgG

Purification: Affinity Purified

Species Reactivity: Rat

Conjugation: Unconjugated

Modification: Unmodified

Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide

Research Areas: Cell Biology

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of DAPK2 in rat spleen lysates using DAPK2 antibody.

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DAPK2 Rabbit mAb

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