Phospho-ERK1/2 (Thr202/Tyr204)/(Thr185/Tyr187) Rabbit mAb

262190

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: N262190

Product Name: Anti-Phospho-ERK1/2 (Thr202/Tyr204)/(Thr185/Tyr187) Rabbit Monoclonal Antibody

Synonyms: MAPK1/MAPK3

UNIPROT ID: P27361/P28482

Background: Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.

Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Thr202/Tyr204 of human Erk1

Applications: WB,IP

Recommended Dilutions: WB: 1/500-1/1000 IP: 1/20

Host Species: Rabbit

Clonality: Rabbit Monoclonal

Clone ID: R04-9E9

MW: Calculated MW: 44,42 kDa; Observed MW: 44,42 kDa

Isotype: IgG

Purification: Affinity Purified

Species Reactivity: Human,Rat

Conjugation: Unconjugated

Modification: Phosphorylated

Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide

Research Areas: NeuroscienceyyyyyPrion disease

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of Erk1 (pT202/pY204)/Erk2 (pT185/pY187) in C6, Hela lysates using Phospho-ERK1/2 (Thr202/Tyr204)/(Thr185/Tyr187) antibody.

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Phospho-ERK1/2 (Thr202/Tyr204)/(Thr185/Tyr187) Rabbit mAb

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