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Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:
Cat.#: N262212 |
Product Name: Anti-KDM2A Rabbit Monoclonal Antibody |
Synonyms: FBL7; CXXC8; FBL11; FBXL11; JHDM1A; LILINA |
UNIPROT ID: Q9Y2K7 |
Background: Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and tri-methylated H3 'Lys-36'. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at the centromere. Required to sustain centromeric integrity and genomic stability, particularly during mitosis. |
Immunogen: A synthetic peptide of human FBXL11 |
Applications: WB,IHC-F,IHC-P,ICC/IF,IP |
Recommended Dilutions: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20 |
Host Species: Rabbit |
Clonality: Rabbit Monoclonal |
Clone ID: R05-4D6 |
MW: Calculated MW: 133 kDa; Observed MW: 133 kDa |
Isotype: IgG |
Purification: Affinity Purified |
Species Reactivity: Human |
Conjugation: Unconjugated |
Modification: Unmodified |
Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide |
Research Areas: Epigenetics and Nuclear Signaling |
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing |
Western blot analysis of FBXL11 in Jurkat lysates using KDM2A antibody. |
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Bioactive Transmembrane Proteins Antibodies for Transmembrane Proteins G Protein | GTPase