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Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:
Cat.#: N262221 |
Product Name: Anti-Fibrillarin Rabbit Monoclonal Antibody |
Synonyms: FIB; FLRN; Nop1; RNU3IP1 |
UNIPROT ID: P22087 |
Background: Fibrillarin is a 2'-O-methyltransferase located in fibrillar regions and Cajal bodies of the nucleolus, where RNA transcription and pre-RNA processing take place. Fibrillarin associates with several other structual proteins as well as box C/D snoRNA to form a complex that functions in pre-rRNA processing, pre-rRNA methylation and ribosome assembly. This complex catalyzes site-specific 2'-O-ribose methylation of targeted nucleotides within the rRNA sequence. The sequence, structure and function of fibrillarin are highly conserved and fibrillarin gene expression is essential for early embryonic development. |
Immunogen: A synthetic peptide of human Fibrillarin |
Applications: WB,IP |
Recommended Dilutions: WB: 1/500-1/1000 IP: 1/20 |
Host Species: Rabbit |
Clonality: Rabbit Monoclonal |
Clone ID: R09-7E5 |
MW: Calculated MW: 34 kDa; Observed MW: 34 kDa |
Isotype: IgG |
Purification: Affinity Purified |
Species Reactivity: Human,Mouse,Rat |
Conjugation: Unconjugated |
Modification: Unmodified |
Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide |
Research Areas: Tags & Cell Markers |
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing |
Western blot analysis of Fibrillarin in K562, C6, 3T3 lysates using Fibrillarin antibody. |
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