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Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:
Cat.#: N262259 | ||
Product Name: Anti-Phospho-Histone H2A.X (Ser139) Rabbit Monoclonal Antibody | ||
Synonyms: H2A.X; H2AFX; H2a/x; HIST5-2AX; Histone H2A.X; gamma H2A.X | ||
UNIPROT ID: P16104 | ||
Background: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. | ||
Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Ser139 of human gamma H2A.X | ||
Applications: WB,IP | ||
Recommended Dilutions: WB: 1/500-1/1000 IP: 1/20 | ||
Host Species: Rabbit | ||
Clonality: Rabbit Monoclonal | ||
Clone ID: R09-4A7 | ||
MW: Calculated MW: 15 kDa; Observed MW: 15 kDa | ||
Isotype: IgG | ||
Purification: Affinity Purified | ||
Species Reactivity: Human,Mouse,Rat | ||
Conjugation: Unconjugated | ||
Modification: Phosphorylated | ||
Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide | ||
Research Areas: Epigenetics and Nuclear Signaling | ||
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||
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