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Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:
Cat.#: N262319 |
Product Name: Anti-HDAC3 Rabbit Monoclonal Antibody |
Synonyms: HDAC3; Histone deacetylase 3; HD3; RPD3-2; SMAP45 |
UNIPROT ID: O15379 |
Background: HDAC3 is a nuclear and cytoplasmic protein that deacetylates both histone (H2A, H3, H4) and non-histone substrates (RelA, SRY, p53, MEF2, PCAF and p300/CBP). HDAC3 deacetylase activity is stimulated by interactions with the N-CoR and SMRT co-repressor proteins. Together, these three proteins form a functional complex that represses transcription associated with nuclear hormone receptors and other transcription factors, including Rev-Erb, COUP-TF, DAX1, MAD and Pit-1. |
Immunogen: A synthetic peptide of human HDAC3 |
Applications: WB,IHC-F,IHC-P,ICC/IF,IP |
Recommended Dilutions: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20 |
Host Species: Rabbit |
Clonality: Rabbit Monoclonal |
Clone ID: R03-4J9 |
MW: Calculated MW: 49 kDa; Observed MW: 49 kDa |
Isotype: IgG |
Purification: Affinity Purified |
Species Reactivity: Human,Mouse,Rat |
Conjugation: Unconjugated |
Modification: Unmodified |
Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide |
Research Areas: Epigenetics and Nuclear Signaling |
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing |
Western blot analysis of HDAC3 in 3T3, Hela, rat Brain lysates using HDAC3 antibody. |
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