KDM1A Rabbit mAb

262444

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: N262444

Product Name: Anti-KDM1A Rabbit Monoclonal Antibody

Synonyms: KDM1A; AOF2; KDM1; KIAA0601; LSD1; Lysine-specific histone demethylase 1A; BRAF35-HDAC complex protein BHC110; Flavin-containing amine oxidase domain-containing protein 2

UNIPROT ID: O60341

Background: Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me. May play a role in the repression of neuronal genes.

Immunogen: A synthetic peptide of human KDM1/LSD1

Applications: WB,ICC/IF,IP

Recommended Dilutions: WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20

Host Species: Rabbit

Clonality: Rabbit Monoclonal

Clone ID: R08-3J5

MW: Calculated MW: 93 kDa; Observed MW: 110 kDa

Isotype: IgG

Purification: Affinity Purified

Species Reactivity: Human,Hamster,Rat

Conjugation: Unconjugated

Modification: Unmodified

Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide

Research Areas: Epigenetics and Nuclear Signaling

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Immunocytochemistry analysis of KDM1/LSD1(green) in Hela using KDM1/LSD1 antibody,and DAPI(blue)	Western blot analysis of KDM1/LSD1 in Jurkat lysates using KDM1A antibody.
Western blot analysis of KDM1/LSD1 in Hela, CHO-K1, C6, Jurkat lysates using KDM1/LSD1 antibody.

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