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Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:
Cat.#: N262480 | ||||
Product Name: Anti-LXR alpha Rabbit Monoclonal Antibody | ||||
Synonyms: NR1H3; LXRA; Oxysterols receptor LXR-alpha; Liver X receptor alpha; Nuclear receptor subfamily 1 group H member 3 | ||||
UNIPROT ID: Q13133 | ||||
Background: Orphan receptor. Interaction with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. LXRES are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides. Plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8. | ||||
Immunogen: A synthetic peptide of human LXR alpha | ||||
Applications: WB,IHC-P | ||||
Recommended Dilutions: WB: 1/500-1/1000 IHC: 1/50-1/100 | ||||
Host Species: Rabbit | ||||
Clonality: Rabbit Monoclonal | ||||
Clone ID: R07-6A4 | ||||
MW: Calculated MW: 50 kDa; Observed MW: 50 kDa | ||||
Isotype: IgG | ||||
Purification: Affinity Purified | ||||
Species Reactivity: Human,Rat | ||||
Conjugation: Unconjugated | ||||
Modification: Unmodified | ||||
Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide | ||||
Research Areas: Cardiovascular | ||||
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||||
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Bioactive Transmembrane Proteins Antibodies for Transmembrane Proteins G Protein | GTPase