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Macro H2A.1 Rabbit mAb

262483

Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:   N262483
Product Name:   Anti-Macro H2A.1 Rabbit Monoclonal Antibody
Synonyms:   H2A.y; H2A/y; mH2A1; H2AF12M; MACROH2A1.1; macroH2A1.2
UNIPROT ID:   O75367
Background:    Involved in stable X chromosome inactivation. Inhibits the binding of transcription factors and interferes with the activity of remodeling SWI/SNF complexes. Inhibits histone acetylation by EP300 and recruits class I HDACs, which induces an hypoacetylated state of chromatin.
Immunogen:    A synthetic peptide of human macroH2A.1
Applications:    WB,ICC/IF
Recommended Dilutions:    WB: 1/500-1/1000 IF: 1/50-1/200
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R04-8E5
MW:    Calculated MW: 40 kDa; Observed MW: 40 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Mouse,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunocytochemistry analysis of macroH2A.1(green) in Hela using macroH2A.1 antibody,and DAPI(blue)

Western blot analysis of macroH2A.1 in rat Brain, C6, 3T3 lysates using Macro H2A.1 antibody.
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