NTH1 Rabbit mAb

262626

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: N262626

Product Name: Anti-NTH1 Rabbit Monoclonal Antibody

Synonyms: FAP3; NTH1; OCTS3; hNTH1

UNIPROT ID: P78549

Background: Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. Has also 8-oxo-7,8-dihydroguanine (8-oxoG) DNA glycosylase activity. Acts preferentially on DNA damage opposite guanine residues in DNA. Is able to process lesions in nucleosomes without requiring or inducing nucleosome disruption.

Immunogen: Recombinant protein of human NTH1

Applications: WB,ICC/IF

Recommended Dilutions: WB: 1/500-1/1000 IF: 1/50-1/200

Host Species: Rabbit

Clonality: Rabbit Monoclonal

Clone ID: R08-8E9

MW: Calculated MW: 34 kDa; Observed MW: 34 kDa

Isotype: IgG

Purification: Affinity Purified

Species Reactivity: Human

Conjugation: Unconjugated

Modification: Unmodified

Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide

Research Areas: Epigenetics and Nuclear Signaling

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of NTH1 in K562, Hela lysates using NTH1 antibody.

Immunocytochemistry analysis of NTH1 (green) in Hela using NTH1 antibody,and DAPI(blue).

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NTH1 Rabbit mAb

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GAPDH Rabbit pAb

TUBA4A Rabbit pAb

ALB Rabbit pAb

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