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p73 Rabbit mAb

262662

Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:   N262662
Product Name:   Anti-p73 Rabbit Monoclonal Antibody
Synonyms:   TP73; P73; Tumor protein p73; p53-like transcription factor; p53-related protein
UNIPROT ID:   O15350
Background:    p73 IS a protein of the p53 family of proteins. Participates in the apoptotic response to DNA damage. Phosphorylated in a cell cycle-dependent manner and negatively regulated by CDKs. When overproduced, activates transcription from p53-responsive promoters and induces apoptosis. May be a tumor suppressor protein. Seven alternatively-spliced isoforms have been described.
Immunogen:    A synthetic peptide of human p73
Applications:    WB,IP,ChIP
Recommended Dilutions:    WB: 1/500-1/1000 IP: 1/20 ChIP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R07-1J7
MW:    Calculated MW: 70 kDa; Observed MW: 80,70 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of p73 in 293 lysates using p73 antibody.
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