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Cadherin Rabbit mAb

262672

Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:   N262672
Product Name:   Anti-Cadherin Rabbit Monoclonal Antibody
Synonyms:   CDHP; CDHE; HJMD; PCAD; CDHN; P-cadherin; E-cadherin; N-cadherin; Cadherin-1; Cadherin-2; Cadherin-3
UNIPROT ID:   P12830/P22223/P19022
Background:    Cadherins are calcium-dependent cell adhesion proteins (PubMed:11976333). They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells (PubMed:11976333). Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.
Immunogen:    A synthetic peptide of human pan Cadherin
Applications:    WB,IHC-F,IHC-P,ICC/IF,IP
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R04-5A8
MW:    Calculated MW: 97 kDa; Observed MW: 130-150 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse,Rat,Hamster
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human Cholangiocarcinoma using pan Cadherin antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Western blot analysis of pan Cadherin in mouse heart, mouse brain lysates using Cadherin antibody.

Western blot analysis of pan Cadherin in Hela, CHO-K1, C6, rat Brain lysates using pan Cadherin antibody.

Immunocytochemistry analysis of pan Cadherin (green) in MCF-7 using pan Cadherin antibody,and DAPI(blue).
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