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PIN1 Rabbit mAb

262718

Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:   N262718
Product Name:   Anti-PIN1 Rabbit Monoclonal Antibody
Synonyms:   DOD; UBL5
UNIPROT ID:   Q13526
Background:    Peptidyl-prolyl cis/trans isomerases (PPIases) catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. This gene encodes one of the PPIases, which specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates. The conformational regulation catalyzed by this PPIase has a profound impact on key proteins involved in the regulation of cell growth, genotoxic and other stress responses, the immune response, induction and maintenance of pluripotency, germ cell development, neuronal differentiation, and survival.
Immunogen:    A synthetic peptide of human Pin1
Applications:    WB,ICC/IF
Recommended Dilutions:    WB: 1/500-1/1000 IF: 1/50-1/200
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R06-4H6
MW:    Calculated MW: 18 kDa; Observed MW: 18 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of Pin1 in K562, rat Brain, C6, 3T3 lysates using Pin1 antibody.

Immunocytochemistry analysis of PIN1 (green) in 293 using PIN1 antibody,and DAPI(blue).
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