PKC beta 1 Rabbit mAb

262725

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: N262725

Product Name: Anti-PKC beta 1 Rabbit Monoclonal Antibody

Synonyms: PRKCB; PKCB; PRKCB2; Protein kinase C beta type; PKC-B; PKC-beta

UNIPROT ID: P05771

Background: Calcium-activated, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase involved in various cellular processes such as regulation of the B-cell receptor (BCR) signalosome, oxidative stress-induced apoptosis, androgen receptor-dependent transcription regulation, insulin signaling and endothelial cells proliferation. Plays a key role in B-cell activation by regulating BCR-induced NF-kappa-B activation. Mediates the activation of the canonical NF-kappa-B pathway (NFKB1) by direct phosphorylation of CARD11/CARMA1 at 'Ser-559', 'Ser-644' and 'Ser-652'.

Immunogen: A synthetic peptide of human PKC beta 2

Applications: WB,ICC/IF,IP

Recommended Dilutions: WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20

Host Species: Rabbit

Clonality: Rabbit Monoclonal

Clone ID: R05-3F4

MW: Calculated MW: 77 kDa; Observed MW: 77 kDa

Isotype: IgG

Purification: Affinity Purified

Species Reactivity: Human,Rat

Conjugation: Unconjugated

Modification: Unmodified

Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide

Research Areas: Signal Transduction

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of PKC beta 1 in K562 lysates using PKC beta 1 antibody	Immunocytochemistry analysis of PKC beta 1 (green) in K562 using PKC beta 1 antibody,and DAPI(blue).
Western blot analysis of PKC beta 1 in rat brain lysates using PKC beta 1 antibody.

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PKC beta 1 Rabbit mAb

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