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Presenilin 1 Rabbit mAb

262756

Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:   N262756
Product Name:   Anti-Presenilin 1 Rabbit Monoclonal Antibody
Synonyms:   PSEN1; AD3; PS1; PSNL1; Presenilin-1; PS-1; Protein S182
UNIPROT ID:   P49768
Background:    Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity.
Immunogen:    A synthetic peptide of human Presenilin 1
Applications:    WB,ICC/IF,IP
Recommended Dilutions:    WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R05-4D4
MW:    Calculated MW: 53 kDa; Observed MW: 20 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    NeuroscienceyyyyyAlzheimer's disease
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of Presenilin 1/PS1 in Hela, C6, Jurkat lysates using Presenilin 1/PS1 antibody

Immunocytochemistry analysis of Presenilin 1 (green) in SKOV-3 using Presenilin 1 antibody,and DAPI(blue).

Western blot analysis of Presenilin 1/PS1 in mouse colon, mouse gastric lysates using Presenilin 1/PS1 antibody.
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