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Prostaglandin D Synthase Rabbit mAb

262763

Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:   N262763
Product Name:   Anti-Prostaglandin D Synthase Rabbit Monoclonal Antibody
Synonyms:   PDS; PGD2; PGDS; LPGDS; PGDS2; L-PGDS
UNIPROT ID:   P41222
Background:    Catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. Involved in a variety of CNS functions, such as sedation, NREM sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes. Binds small non-substrate lipophilic molecules, including biliverdin, bilirubin, retinal, retinoic acid and thyroid hormone, and may act as a scavenger for harmful hydrophopic molecules and as a secretory retinoid and thyroid hormone transporter. Possibly involved in development and maintenance of the blood-brain, blood-retina, blood-aqueous humor and blood-Tis barrier. It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system.
Immunogen:    A synthetic peptide of human Prostaglandin D Synthase
Applications:    WB,IHC-F,IHC-P,ICC/IF
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R06-1C5
MW:    Calculated MW: 21 kDa; Observed MW: 26 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human lung cancer tissue using Prostaglandin D Synthase antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Immunocytochemistry analysis of Prostaglandin D Synthase (green) in K562 using Prostaglandin D Synthase antibody,and DAPI(blue).

Western blot analysis of Prostaglandin D Synthase in K562, C6, 3T3, Hela lysates using Prostaglandin D Synthase antibody.
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