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Proteasome alpha 6 Rabbit mAb

262767

Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:   N262767
Product Name:   Anti-Proteasome alpha 6 Rabbit Monoclonal Antibody
Synonyms:   proteasome subunit alpha 6; IOTA; p27K; PROS27
UNIPROT ID:   P60900
Background:    The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple transcript variants encoding several different isoforms have been found for this gene. A pseudogene has been identified on the Y chromosome. [provided by RefSeq, Aug 2013]
Immunogen:    A synthetic peptide of human Proteasome subunit alpha type 6
Applications:    WB,ICC/IF
Recommended Dilutions:    WB: 1/500-1/1000 IF: 1/50-1/200
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R01-4I2
MW:    Calculated MW: 27 kDa; Observed MW: 27 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunocytochemistry analysis of Proteasome subunit alpha type 6 (green) in Hela using Proteasome subunit alpha type 6 antibody,and DAPI(blue)

Western blot analysis of Proteasome subunit alpha type 6 in K562, C6, 3T3, Hela lysates using Proteasome alpha 6 antibody.
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