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Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:
Cat.#: N262782 | ||
Product Name: Anti-PTN Rabbit Monoclonal Antibody | ||
Synonyms: PTN; HBNF1; NEGF1; Pleiotrophin; PTN; Heparin-binding brain mitogen; HBBM; Heparin-binding growth factor 8; HBGF-8; Heparin-binding growth-associated molecule; HB-GAM; Heparin-binding neurite outgrowth-promoting factor 1; HBNF-1; Osteoblast-specific factor 1; OSF-1 | ||
UNIPROT ID: P21246 | ||
Background: Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells (PubMed:1768439, PubMed:1733956). Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti-apoptotic signaling of PTN and regulation of cell proliferation (PubMed:11278720). Binds to cell-surface target proteins via their chondroitin sulfate groups (PubMed:26896299). Down-regulates PTPRZ1 activity (PubMed:16814777). | ||
Immunogen: A synthetic peptide of human PTN | ||
Applications: WB,IP | ||
Recommended Dilutions: WB: 1/500-1/1000 IP: 1/20 | ||
Host Species: Rabbit | ||
Clonality: Rabbit Monoclonal | ||
Clone ID: R01-2J3 | ||
MW: Calculated MW: 19 kDa; Observed MW: 19 kDa | ||
Isotype: IgG | ||
Purification: Affinity Purified | ||
Species Reactivity: Human,Rat | ||
Conjugation: Unconjugated | ||
Modification: Unmodified | ||
Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide | ||
Research Areas: Neuroscience | ||
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||
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Bioactive Transmembrane Proteins Antibodies for Transmembrane Proteins G Protein | GTPase