Rb Rabbit mAb

262823

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: N262823

Product Name: Anti-Rb Rabbit Monoclonal Antibody

Synonyms: RB1; Retinoblastoma-associated protein; p105-Rb; pRb; Rb; pp110

UNIPROT ID: P06400

Background: Cell cycle-dependent phosphorylation by a CDK inhibits Rb target binding and allows cell cycle progression. Rb inactivation and subsequent cell cycle progression likely requires an initial phosphorylation by cyclin D-CDK4/6 followed by cyclin E-CDK2 phosphorylation. Specificity of different CDK/cyclin complexes has been observed in vitro and cyclin D1 is required for Ser780 phosphorylation in vivo.

Immunogen: A synthetic peptide of human Rb

Applications: WB,ICC/IF,IP

Recommended Dilutions: WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20

Host Species: Rabbit

Clonality: Rabbit Monoclonal

Clone ID: R09-4H8

MW: Calculated MW: 106 kDa; Observed MW: 110 kDa

Isotype: IgG

Purification: Affinity Purified

Species Reactivity: Human

Conjugation: Unconjugated

Modification: Unmodified

Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide

Research Areas: Cell Biology

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Immunocytochemistry analysis of Rb(green) in Hela using Rb antibody,and DAPI(blue)

Western blot analysis of Rb in 3T3 lysates using Rb antibody.

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Product Targets

Product Categories

Rb Rabbit mAb

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