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Thyroid Transcription Factor 1 Rabbit mAb

263035

Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:   N263035
Product Name:   Anti-Thyroid Transcription Factor 1 Rabbit Monoclonal Antibody
Synonyms:   NKX2-1; NKX2A; TITF1; TTF1; Homeobox protein Nkx-2.1; Homeobox protein NK-2 homolog A; Thyroid nuclear factor 1; Thyroid transcription factor 1; TTF-1
UNIPROT ID:   P43699
Background:    This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer.
Immunogen:    A synthetic peptide of human TTF1
Applications:    WB,ICC/IF
Recommended Dilutions:    WB: 1/500-1/1000 IF: 1/50-1/200
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R09-1H7
MW:    Calculated MW: 39 kDa; Observed MW: 39 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Hamster
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of TTF1 in K562, CHO-K1, Hela lysates using TTF1 antibody.

Immunocytochemistry analysis of Thyroid Transcription Factor 1 (green) in K562 using Thyroid Transcription Factor 1 antibody,and DAPI(blue).
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