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Thioredoxin Reductase 1 Rabbit mAb

263041

Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:   N263041
Product Name:   Anti-Thioredoxin Reductase 1 Rabbit Monoclonal Antibody
Synonyms:   TR; TR1; TXNR; TRXR1; GRIM-12
UNIPROT ID:   Q16881
Background:    Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid.
Immunogen:    Recombinant protein of human TXNRD1
Applications:    WB,IHC-F,IHC-P,ICC/IF,IP
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R01-8I4
MW:    Calculated MW: 71 kDa; Observed MW: 55 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human lung cancer using TXNRD1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Western blot analysis of TXNRD1 in 3T3 lysates using Thioredoxin Reductase 1 antibody.

Western blot analysis of TXNRD1 in K562, Hela lysates using TXNRD1 antibody.

Immunocytochemistry analysis of TXNRD1(green) in Hela using TXNRD1 antibody,and DAPI(blue).
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