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Wnt5a Rabbit mAb

263085

Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:   N263085
Product Name:   Anti-Wnt5a Rabbit Monoclonal Antibody
Synonyms:   WNT5A; Protein Wnt-5a
UNIPROT ID:   P41221
Background:    Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta-catenin-induced reporter gene expression.
Immunogen:    A synthetic peptide of human Wnt5a
Applications:    WB,ICC/IF
Recommended Dilutions:    WB: 1/500-1/1000 IF: 1/50-1/200
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R08-4A3
MW:    Calculated MW: 42 kDa; Observed MW: 45 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunocytochemistry analysis of Wnt5a (green) in hela using Wnt5a antibody,and DAPI(blue)

Western blot analysis of Wnt5a in Hela lysates using Wnt5a antibody.
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