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Phospho-YAP1 (Ser127) Rabbit mAb

263091

Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:   N263091
Product Name:   Anti-Phospho-YAP1 (Ser127) Rabbit Monoclonal Antibody
Synonyms:   YAP1; YAP65; Yorkie homolog; 65 kDa Yes-associated protein; YAP65
UNIPROT ID:   P46937
Background:    YAP (Yes-associated protein, YAP65) was identified based on its ability to associate with the SH3 domain of Yes. Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.
Immunogen:    A synthetic phosphopeptide corresponding to residues surrounding Ser127 of human YAP1
Applications:    WB,IHC-P
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R07-6C2
MW:    Calculated MW: 54 kDa; Observed MW: 70-75 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Phosphorylated
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of Phospho-YAP1 (Ser127) in Hela, Hela+CalyculinA lysates using Phospho-YAP1 (Ser127) antibody.
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