RYK Rabbit mAb

263113

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: N263113

Product Name: Anti-RYK Rabbit Monoclonal Antibody

Synonyms: ERK 3; JTK5; JTK5A; Ryk; RYK1; Vik

UNIPROT ID: P34925

Background: May be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A. Involved in neuron differentiation, axon guidance, corpus callosum establishment and neurite outgrowth. In response to WNT3 stimulation, receptor C-terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellular product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development.

Immunogen: A synthetic peptide of human RYK

Applications: WB,IHC-F,IHC-P,ICC/IF,IP

Recommended Dilutions: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20

Host Species: Rabbit

Clonality: Rabbit Monoclonal

Clone ID: R03-4E1

MW: Calculated MW: 68 kDa; Observed MW: 72 kDa

Isotype: IgG

Purification: Affinity Purified

Species Reactivity: Human

Conjugation: Unconjugated

Modification: Unmodified

Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide

Research Areas: -

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human lung cancer using RYK antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.	Western blot analysis of RYK in Hela, A549, HL-60, U2OS, U87-MG lysates using RYK antibody.
Immunocytochemistry analysis of RYK (green) in hela using RYK antibody,and DAPI(blue)

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