Phospho-AKT1 (Thr450) Rabbit mAb

263148

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: N263148

Product Name: Anti-Phospho-AKT1 (Thr450) Rabbit Monoclonal Antibody

Synonyms: AKT1; PKB; RAC; RAC-alpha serine/threonine-protein kinase; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alpha

UNIPROT ID: P31749

Background: Akt, also referred to as PKB or Rac, plays a critical role in controlling survival and apoptosis. This protein kinase is activated by insulin and various growth and survival factors to function in a wortmannin-sensitive pathway involving PI3 kinase. Akt is activated by phospholipid binding and activation loop phosphorylation at Thr308 by PDK1 and by phosphorylation within the carboxy terminus at Ser473.

Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Thr450 of human AKT1

Applications: WB,IP

Recommended Dilutions: WB: 1/500-1/1000 IP: 1/20

Host Species: Rabbit

Clonality: Rabbit Monoclonal

Clone ID: R07-4A7

MW: Calculated MW: 56 kDa; Observed MW: 56 kDa

Isotype: IgG

Purification: Affinity Purified

Species Reactivity: Human,Rat

Conjugation: Unconjugated

Modification: Phosphorylated

Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide

Research Areas: Neuroscience

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of Phospho-AKT1 (Thr450) in U2OS, C6 lysates using Phospho-AKT1 (Thr450) antibody.

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Phospho-AKT1 (Thr450) Rabbit mAb

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