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Phospho-Amyloid Precursor Protein (Thr743) Rabbit mAb

263150

Size:100 μl Price:$ 349 Brand:NewEast Place of Origin:USA Immunogen:

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Cat.#:   N263150
Product Name:   Anti-Phospho-Amyloid Precursor Protein (Thr743) Rabbit Monoclonal Antibody
Synonyms:   APP; A4; AD1; Amyloid beta A4 protein; ABPP; APPI; APP; Alzheimer disease amyloid protein; Cerebral vascular amyloid peptide; CVAP; PreA4; Protease nexin-II; PN-II
UNIPROT ID:   P05067
Background:    APP a cell surface receptor that influences neurite growth, neuronal adhesion and axonogenesis. Cleaved by secretases to form a number of peptides, some of which bind to the acetyltransferase complex Fe65/TIP60 to promote transcriptional activation.
Immunogen:    A synthetic phosphopeptide corresponding to residues surrounding Thr743 of human Amyloid Precursor Protein
Applications:    WB,ICC/IF,IP
Recommended Dilutions:    WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R07-4D0
MW:    Calculated MW: 87 kDa; Observed MW: 100 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Rat
Conjugation:    Unconjugated
Modification:    Phosphorylated
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    NeuroscienceyyyyyAlzheimer's disease
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of Phospho-Amyloid Precursor Protein (Thr743) in Hela, U2OS, C6 lysates using Phospho-Amyloid Precursor Protein (Thr743) antibody.

Immunocytochemistry analysis of Phospho-Amyloid Precursor Protein (Thr743) (green) in LNcap using Phospho-Amyloid Precursor Protein (Thr743) antibody,and DAPI(blue).
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