Phospho-MEK4 (Ser80) Rabbit mAb

263177

Size：100 μl Price：$ 349 Brand：NewEast Place of Origin：USA Immunogen：

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Cat.#: N263177

Product Name: Anti-Phospho-MEK4 (Ser80) Rabbit Monoclonal Antibody

Synonyms: MAP2K4; JNKK1; MEK4; MKK4; PRKMK4; SEK1; SERK1; SKK1; Dual specificity mitogen-activated protein kinase kinase 4; MAP kinase kinase 4; MAPKK 4; JNK-activating kinase 1; MAPK/ERK kinase 4; MEK 4; SAPK/ERK kinase 1; SEK1; Stress-activated pro

UNIPROT ID: P45985

Background: This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. They form a three-tiered signaling module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues. A similar protein in mouse has been reported to play a role in liver organogenesis. A pseudogene of this gene is located on the long arm of chromosome X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Ser80 of human MEK4/MKK4

Applications: WB,IP

Recommended Dilutions: WB: 1/500-1/1000 IP: 1/20

Host Species: Rabbit

Clonality: Rabbit Monoclonal

Clone ID: R03-5C4

MW: Calculated MW: 44 kDa; Observed MW: 44 kDa

Isotype: IgG

Purification: Affinity Purified

Species Reactivity: Human

Conjugation: Unconjugated

Modification: Phosphorylated

Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide

Research Areas: Signal Transduction

Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of Phospho-MEK4/MKK4 (Ser80) in A549, MCF-7, U251 lysates using Phospho-MEK4/MKK4 (Ser80) antibody.

Western blot analysis of Phospho-MEK4/MKK4 (Ser80) in 3T3 lysates using Phospho-MEK4 (Ser80) antibody.

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Phospho-MEK4 (Ser80) Rabbit mAb

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